NGS Kits

Paving the way forward in cancer diagnostics

GeneFirst's next generation sequencing kits are based on our proprietary ATOM-Seq technology.

ATOM-Seq (Adaptor Template Oligonucleotide Mediated-sequencing) overcomes limitations associated with inefficiencies, complexities and low sensitivities of next generation sequencing. It offers advantage of a unique, efficient, and robust way of adding molecular barcodes directly onto target samples, avoiding pitfalls of current PCR- and ligation- based methods. It is capable of using minimal input material (DNA, RNA, or a combination of DNA+RNA). Our proprietary approach allows for identification of combinations of mutations including SNPs, indels, insertions, and fusions simultaneously, as well as being perfectly suited for detecting mutations in DNA isolated from liquid biopsies such as those found in circulating tumour DNA (ctDNA).

Novel NGS Technology

  • Patented approach — Adaptor Template Oligonucleotide Mediated - sequencing (ATOM-Seq)

  • Novel approach for molecular barcoding, followed by PCR to selectively enrich target regions of interest

  • Adaptable to any sequencing platform

Unparalleled Innovation

  • High sensitivity including sequencing error elimination

  • Minimal input DNA required

  • High efficiency with a unique method of adding molecular barcodes

  • Simple, streamlined and fast workflow

Improving Healthcare

  • Early and sensitive detection for improved disease monitoring

  • Decreased turnaround time from sample-in to results-out

  • Non-invasive method for tumour mutation profiling

  • Allow better stratification of patient care pathway

  • Support therapeutic discovery and development

+44 (0) 1865 407400

Culham Science Centre, Oxfordshire, UK.  OX14 3DB

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