Phosphatidylinositol 3-kinases are a family of intracellular signal transducers involved in cell growth, proliferation, differentiation, motility, apoptosis etc. Activating mutations of PIK3 catalytic subunit are found in several types of cancer, including colorectal cancer, gastric cancer, lung cancer, brain cancer, endometrial cancer, ovarian cancer, breast cancer.

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PIK3CA-MMD-PCR Mutation Test Kit enables in one closed-tube reaction detection of four different PIK3CA mutations against a background of wild-type genomic DNA.

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The kit allows distinguishing mutations in exon 9 (detected in FAM channel) from mutation in exon 20 (detected in HEX channel).