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XCeloSeq  Colon Cancer cfDNA Kit

®

NGS Library Preparation kit for use with cell-free DNA from liquid biopsy

Use ATOM-Seq to capture cell-free DNA and enrich for mutation hotspots across 22 genes frequently mutated in colon cancer and 5 important DPYD SNPs for detection of the even the rarest mutations.

Product Details

Specifications

 Home  >  ATOM-Seq Capture Chemistry  >  Cell-free DNA Enrichment Workflow > XCeloSeq Colon Cancer cfDNA Kit

%Targeting primers are split between pool 1 which enriches sense DNA and pool 2 which enriches antisense DNA.

*Higher quantities will improve maximum sensitivity.

Target Genes

Targets mutation hotspots across 22 genes most frequently mutated in colon cancers and DPYD

*Whole coding region coverage (NM_000546)

DPYD variants rs67376798, DPYD*A2 (rs3918290), rs55886062 and HapB3 (rs75017182, rs56038477) are covered.

 

Please contact us to discuss customising this panel.

 

Read about all our customisation options here.

Benefits

Capture more of your patient sample with ATOM-Seq which captures all single stranded, double-stranded or nicked DNA of any length. 

Detect even the rarest clinical signatures by using both UMIs and unique, error-reducing workflow optimisations

Simple, single-day protocols leveraging the inherent simplicity and efficiency of DNA polymerases

Unique Dual Indexes

Unique Dual Indexes (UDIs) are required to be purchased and are sold separately

Please contact us to discuss additional index options.

Resources

Product insert

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SEQ009 Product Insert

For Research Use Only (RUO).

Not for use in diagnostic procedures. Not intended to be used for treatment of human or animal diseases.

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